ZC3H8 antibody (N-Term)

Catalog No. ABIN655410

Product Details anti-ZC3H8 Antibody

Target: ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))

Binding Specificity: AA 52-81, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZC3H8 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ZC3H8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human ZC3H8.

Clone: RB28955

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ZC3H8

Target: ZC3H8 (Zinc Finger CCCH-Type Containing 8 (ZC3H8))

Alternative Name: ZC3H8 (ZC3H8 Products)

Synonyms: Zc3hdc8 antibody, DKFZp459D018 antibody, AU020882 antibody, E130108N08Rik antibody, Fliz1 antibody, ZC3HDC8 antibody, zinc finger CCCH type containing 8 antibody, zinc finger CCCH-type containing 8 antibody, Zc3h8 antibody, ZC3H8 antibody

Background: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis.

Molecular Weight: 33576

Gene ID: 84524

NCBI Accession: NP_115883

UniProt: Q8N5P1