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Deoxynucleotidyltransferase, terminal (DNTT) (AA 438-467), (C-Term) antibody

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Synonyms TdT, TDT, BB160593, Tdt, dntt-A, dntt
AA 438-467, C-Term
(38), (34), (16), (15), (13), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
(144), (29), (22), (7), (5), (3), (2), (1)
(118), (31)
Clonality (Clone)
Polyclonal ()
(10), (8), (5), (4), (4), (4), (1), (1), (1)
Western Blotting (WB)
(95), (50), (28), (14), (14), (11), (10), (5), (5), (4), (2), (2), (2), (1), (1)
Pubmed 1 reference available
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Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This TdT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 AA from the C-terminal region of human TdT.
Clone RB18827
Isotype Ig
Specificity This TdT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-475 amino acids from the C-terminal region of human TdT.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TdT (DNTT Antibody Abstract)
Background This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Synonyms: DNA nucleotidylexotransferase,DNTT,TDT
Molecular Weight 58536 DA
Gene ID 1791
NCBI Accession NP_004079, NP_001017520
UniProt P04053
Research Area Cell Structure, Signaling, Protein Modifications, Chromatin
Pathways DNA Damage Repair
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 438-467), (C-Term) antibody (ABIN655508) TdT Antibody (C-term) (ABIN655508) western blot analysis in K562 cell line lysates (3...
Background publications Liu, McGavran, Lovell et al.: "Nonpositive terminal deoxynucleotidyl transferase in pediatric precursor B-lymphoblastic leukemia." in: American journal of clinical pathology, Vol. 121, Issue 6, pp. 810-5, 2004 (PubMed).

Catalog No. ABIN655508
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