You are viewing an incomplete version of our website. Please click to reload the website as full version.

Deoxynucleotidyltransferase, terminal (DNTT) (AA 438-467), (C-Term) antibody

Details for Product No. ABIN655508, Supplier: Log in to see
Antigen
  • TdT
  • TDT
  • BB160593
  • Tdt
  • dntt-A
  • dntt
Alternatives
anti-Human Deoxynucleotidyltransferase, terminal antibody for Immunohistochemistry
Epitope
AA 438-467, C-Term
37
33
16
15
9
3
3
3
2
2
2
2
2
2
1
1
1
Reactivity
Human
132
31
24
7
5
3
2
1
Host
Rabbit
109
29
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
10
7
5
4
4
4
1
1
1
Application
Western Blotting (WB)
93
50
22
14
10
9
6
4
4
4
2
2
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This TdT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 438-467 AA from the C-terminal region of human TdT.
Clone RB18827
Isotype Ig
Specificity This TdT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-475 amino acids from the C-terminal region of human TdT.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TdT (DNTT Antibody Abstract)
Background This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Synonyms: DNA nucleotidylexotransferase,DNTT,TDT
Molecular Weight 58536 DA
Gene ID 1791
NCBI Accession NP_004079, NP_001017520
UniProt P04053
Research Area Cell Structure, Signaling, Protein Modifications, Chromatin
Pathways DNA Damage Repair
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Deoxynucleotidyltransferase, terminal (DNTT) (AA 438-467), (C-Term) antibody (ABIN655508) TdT Antibody (C-term) (ABIN655508) western blot analysis in K562 cell line lysates (3...
Background publications Liu, McGavran, Lovell et al.: "Nonpositive terminal deoxynucleotidyl transferase in pediatric precursor B-lymphoblastic leukemia." in: American journal of clinical pathology, Vol. 121, Issue 6, pp. 810-5, 2004 (PubMed).