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Details for Product No. ABIN655590

Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 5 (LILRA5) (N-Term), (AA 56-85) antibody

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Antigen
Synonyms CD85, CD85F, ILT-11, ILT11, LILRB7, LIR-9, LIR9, E030017K20, EG232801, Gm4878, Lilrc1
Epitope
»Alternatives N-Term, AA 56-85
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN655590
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This LILRA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-85 AA from the N-terminal region of human LILRA5.
Clone RB30159
Isotype Ig
Specificity This LILRA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-93 amino acids from the N-terminal region of human LILRA5.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LILRA5
Background The protein encoded by this gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].
Synonyms: Leukocyte immunoglobulin-like receptor subfamily A member 5,LILRA5,ILT11, LILRB7, LIR9
Molecular Weight 32755 DA
Gene ID 353514
UniProt NP_871715.1, NP_067073.1, NP_871714.1, NP_870994.1, A6NI73
Research Area Cell Structure, Protein Modifications, Cell Signaling
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Borges, Kubin, Kuhlman: "LIR9, an immunoglobulin-superfamily-activating receptor, is expressed as a transmembrane and as a secreted molecule." in: Blood, Vol. 101, Issue 4, pp. 1484-6, 2003 (PubMed).

Shiroishi, Kajikawa, Kuroki et al.: "Crystal structure of the human monocyte-activating receptor, "Group 2" leukocyte Ig-like receptor A5 (LILRA5/LIR9/ILT11)." in: The Journal of biological chemistry, Vol. 281, Issue 28, pp. 19536-44, 2006 (PubMed).

Alternatives for antigen "Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 5 (LILRA5)", type "Antibodies"
Hosts (7), (1), (1), (1)
Reactivities (8), (1), (1)
Applications (9), (4), (1), (1)
Conjugates (1), (1)
Epitopes (5), (2), (2), (1)
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