Parvin, beta (PARVB) (N-Term) antibody

Antigen: Parvin, beta (PARVB)

Synonyms: CGI-56, D15Gsk1, AI595373, AW742462, fd02e01, zgc:73117, wu:fd02e01, parvb, MGC69390, PARVB, MGC143245, MGC115486

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655719

Additional Information

Alternative name: PARVB

Gene ID: 29780

UniProt: NP_037459.2, Q9HBI1, NP_001003828.1

Immunogen: This PARVB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-99 amino acids from the N-terminal region of human PARVB.

Isotype: Ig

Description: Other names: PARVB,Beta-parvin,

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This PARVB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-99 amino acids from the N-terminal region of human PARVB.

Molecular Weight: 41714 DA

Comments:

Background: Members of the parvin family, including PARVB, are actin-binding proteins associated with focal contacts.[supplied by OMIM].

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Phospho-specific antibodies, Cell Structure, Protein Modifications

Restrictions: For Research Use only

Publications

Product: Johnstone, Mongroo, Rich et al.: "Parvin-beta inhibits breast cancer tumorigenicity and promotes CDK9-mediated peroxisome proliferator-activated receptor gamma 1 phosphorylation." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 687-704, 2008 (PubMed).

Matsuda, Kameyama, Suzuki et al.: "Affixin activates Rac1 via betaPIX in C2C12 myoblast." in: FEBS letters, Vol. 582, Issue 8, pp. 1189-96, 2008 (PubMed).

Kimura, Murakami, Kizaka-Kondoh et al.: "Functional molecular imaging of ILK-mediated Akt/PKB signaling cascades and the associated role of beta-parvin." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 747-55, 2010 (PubMed).

Wu, Ng, Chen et al.: "Expression of parvin-beta is a prognostic factor for patients with urothelial cell carcinoma of the upper urinary tract." in: British journal of cancer, Vol. 103, Issue 6, pp. 852-60, 2010 (PubMed).