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IER3 antibody (Immediate Early Response 3) (AA 38-65)

Details for Product anti-IER3 Antibody No. ABIN655735, Supplier: Log in to see
Antigen
  • AI663993
  • cI-3
  • DIF-2
  • Dif2
  • DIF2
  • gly96
  • GLY96
  • IER3
  • IEX-1
  • IEX-1L
  • Iex1
  • IEX1
  • Ler3
  • Prg1
  • PRG1
Epitope
AA 38-65, N-Term
15
14
4
4
2
1
Reactivity
Human, Mouse (Murine)
46
26
15
Host
Rabbit
46
Clonality (Clone)
Polyclonal ()
Conjugate
This IER3 antibody is un-conjugated
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
33
23
20
15
12
11
11
8
2
Supplier
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Immunogen This IER3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 AA from the N-terminal region of human IER3.
Clone RB20475
Isotype Ig
Specificity This IER3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-73 amino acids from the N-terminal region of human IER3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name IER3 (IER3 Antibody Abstract)
Background This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not generate a valid protein.
Synonyms: IER3,Radiation-inducible immediate-early gene IEX-1,DIF2, IEX1, PRG1
Molecular Weight 16929 DA
Gene ID 8870
NCBI Accession NP_003888
UniProt P46695
Research Area Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000, IHC (p) = 1:50-100, IF = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.36 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-IER3 antibody (Immediate Early Response 3) (AA 38-65) (ABIN655735) IER3 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lan...
Western Blotting (WB) image for anti-IER3 antibody (Immediate Early Response 3) (AA 38-65) (ABIN655735) IER3 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).T...
Immunohistochemistry (IHC) image for anti-IER3 antibody (Immediate Early Response 3) (AA 38-65) (ABIN655735) IER3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin e...
Immunofluorescence (IF) image for anti-IER3 antibody (Immediate Early Response 3) (AA 38-65) (ABIN655735) Confocal immunofluorescent analysis of IER3 Antibody (N-term) with A549 cell followed...
Flow Cytometry (FACS) image for anti-IER3 antibody (Immediate Early Response 3) (AA 38-65) (ABIN655735) IER3 Antibody (N-term) flow cytometric analysis of A549 cells (right histogram) comp...
Product cited in: Chen, Huang, Nakatsu, Xue, Deng, Fan: "Identification of novel molecular markers through transcriptomic analysis in human fetal and adult corneal endothelial cells." in: Human molecular genetics, Vol. 22, Issue 7, pp. 1271-9, 2013 (PubMed).

Background publications Fellay, Ge, Shianna, Colombo, Ledergerber, Cirulli, Urban, Zhang, Gumbs, Smith, Castagna, Cozzi-Lepri, De Luca, Easterbrook, Günthard, Mallal, Mussini, Dalmau, Martinez-Picado, Miro, Obel, Wolinsky, Martinson, Detels, Margolick, Jacobson, Descombes, Anton: "Common genetic variation and the control of HIV-1 in humans." in: PLoS genetics, Vol. 5, Issue 12, pp. e1000791, 2009 (PubMed).

Do, Ucisik-Akkaya, Davis, Morrison, Dorak: "TP53 R72P and MDM2 SNP309 polymorphisms in modification of childhood acute lymphoblastic leukemia susceptibility." in: Cancer genetics and cytogenetics, Vol. 195, Issue 1, pp. 31-6, 2009 (PubMed).