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Details for Product No. ABIN655792

Suppressor of Cytokine Signaling 4 (SOCS4) (AA 227-254), (Center) antibody

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Antigen
Synonyms SOCS7, 3110032M18Rik, A730004F22Rik, AI427843, AU015727, AU015859, Socs7, SOCS6, socs4, SOCS4, Socs4, socs6l, zgc:64107, wu:fb77f06, socs7, socs4a
Epitope
»Alternatives AA 227-254, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Pubmed 1 reference available
Catalog no. ABIN655792
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 AA from the Central region of human SOCS4.
Clone RB31389
Isotype Ig
Specificity This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-262 amino acids from the Central region of human SOCS4.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SOCS4
Background The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms: SOCS4,Suppressor of cytokine signaling 4,SOCS7
Pathways: Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus
Molecular Weight 50623 Da
Gene ID 122809
UniProt Q8WXH5
Research Area Cell Signaling, Cell Cycle, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Alternatives for antigen "Suppressor of Cytokine Signaling 4 (SOCS4)", type "Antibodies"
Hosts (14), (7), (3)
Reactivities (21), (3), (2)
Applications (18), (12), (10), (7), (3), (2), (2), (1), (1), (1), (1), (1)
Epitopes (7), (3), (2), (1), (1), (1)
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