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SOCS4 antibody (Suppressor of Cytokine Signaling 4) (AA 227-254)

Details for Product anti-SOCS4 Antibody No. ABIN655792, Supplier: Log in to see
Antigen
  • socs4
  • SOCS4
  • SOCS6
  • Socs4
  • socs6l
  • zgc:64107
  • wu:fb77f06
  • socs7
  • socs4a
  • SOCS7
  • 3110032M18Rik
  • A730004F22Rik
  • AI427843
  • AU015727
  • AU015859
  • Socs7
Alternatives
anti-Human SOCS4 antibody for ELISA
Epitope
AA 227-254, Center
27
22
21
16
15
5
3
3
2
2
2
1
1
1
Reactivity
Human
82
4
4
3
1
1
1
Host
Rabbit
62
17
5
Clonality (Clone)
Polyclonal ()
Conjugate
This SOCS4 antibody is un-conjugated
5
5
5
5
5
5
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
63
50
23
17
11
8
6
2
1
1
Supplier
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Immunogen This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 AA from the Central region of human SOCS4.
Clone RB31389
Isotype Ig
Specificity This SOCS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-262 amino acids from the Central region of human SOCS4.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SOCS4 (SOCS4 Antibody Abstract)
Background The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms: SOCS4,Suppressor of cytokine signaling 4,SOCS7
Pathways: Insulin signaling pathway, Jak-STAT signaling pathway, Type II diabetes mellitus
Molecular Weight 50623 Da
Gene ID 122809
UniProt Q8WXH5
Research Area Cell Signaling, Cell Cycle, Cell Structure
Pathways JAK-STAT Signaling, EGFR Signaling Pathway
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-SOCS4 antibody (Suppressor of Cytokine Signaling 4) (AA 227-254) (ABIN655792) SOCS4 Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane)...
Immunohistochemistry (IHC) image for anti-SOCS4 antibody (Suppressor of Cytokine Signaling 4) (AA 227-254) (ABIN655792) SOCS4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin ...
Immunofluorescence (IF) image for anti-SOCS4 antibody (Suppressor of Cytokine Signaling 4) (AA 227-254) (ABIN655792) Confocal immunofluorescent analysis of SOCS4 Antibody (Center) with A2058 cell follow...
Background publications Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).