Frequently Rearranged in Advanced T-Cell Lymphomas 2 (FRAT2) (C-Term), (AA 203-230) antibody

Details for Product No. ABIN655793
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Antigen
Synonyms FRAT2
Epitope
C-Term, AA 203-230
(12), (8), (1), (1), (1), (1)
Reactivity
Human
(30), (12), (12), (12), (12)
Host
Rabbit
(22), (6), (1), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)
(18), (10), (10), (8), (7), (5), (3), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN655793
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Immunogen This FRAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 AA from the C-terminal region of human FRAT2.
Clone RB31392
Isotype Ig
Specificity This FRAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-233 amino acids from the C-terminal region of human FRAT2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FRAT2
Background The protein encoded by this intronless gene belongs to the GSK-3-binding protein family. Studies show that this protein plays a role as a positive regulator of the WNT signaling pathway. It may be upregulated in tumor progression.
Synonyms: FRAT2,GSK-3-binding protein FRAT2,
Molecular Weight 24051 DA
Gene ID 23401
NCBI Accession NP_036215
UniProt O75474
Research Area Cell Signaling, Cell Structure
Application Notes IHC = 1:10-50, WB = 1:1000, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Frequently Rearranged in Advanced T-Cell Lymphomas 2 (FRAT2) (C-Term), (AA 203-230) antibody Confocal immunofluorescent analysis of FRAT2 Antibody (C-term) with ZR-75-1 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
anti-Frequently Rearranged in Advanced T-Cell Lymphomas 2 (FRAT2) (C-Term), (AA 203-230) antibody (2) FRAT2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human bladder carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FRAT2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-Frequently Rearranged in Advanced T-Cell Lymphomas 2 (FRAT2) (C-Term), (AA 203-230) antibody (3) FRAT2 Antibody (C-term) western blot analysis in ZR-75-1,K562 cell line lysates (35ug/lane).This demonstrates the FRAT2 antibody detected the FRAT2 protein (arrow).
Background publications Deloukas, Earthrowl, Grafham et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, 2004 (PubMed).

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