anti-IRF9 antibody (Interferon Regulatory Factor 9) (AA 75-104)

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Antigen
Synonyms IRF-9, ISGF3, ISGF3G, p48, zgc:92097, Irf-9, Isgf3g
Alternatives
Epitope
AA 75-104, N-Term
(13), (10), (9), (6), (5), (3), (3), (2), (1), (1), (1), (1)
Reactivity
Mouse (Murine)
(56), (19), (5), (1), (1), (1), (1)
Host
Rabbit
(49), (13), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
This IRF9 antibody is un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(47), (23), (23), (14), (11), (10), (10), (4), (2)
Pubmed 2 references available
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Quantity 400 μL
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Immunogen This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 AA from the N-terminal region of human IRF9.
Clone RB19229
Isotype Ig
Specificity This IRF9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-112 amino acids from the N-terminal region of human IRF9.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name IRF9 (IRF9 Antibody Abstract)
Background IRF9 is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Synonyms: Interferon regulatory factor 9,IRF9,ISGF3G
Molecular Weight 43696 DA
Gene ID 10379
NCBI Accession NP_006075
UniProt Q00978
Research Area Translation Factors, Transcription Factors, Signaling, Cell Structure
Pathways JAK-STAT Signaling, Interferon-gamma Pathway
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.28 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-IRF9 antibody (Interferon Regulatory Factor 9) (AA 75-104) (ABIN655818) IRF9 Antibody (N-term) western blot analysis in mouse spleen tissue lysates (35ug/la...
Immunohistochemistry (IHC) image for anti-IRF9 antibody (Interferon Regulatory Factor 9) (AA 75-104) (ABIN655818) IRF9 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin e...
Immunofluorescence (IF) image for anti-IRF9 antibody (Interferon Regulatory Factor 9) (AA 75-104) (ABIN655818) Confocal immunofluorescent analysis of IRF9 Antibody (N-term) with Hela cell followed...
Background publications Jugessur, Shi, Gjessing et al.: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).

Mosbruger, Duggal, Goedert et al.: "Large-scale candidate gene analysis of spontaneous clearance of hepatitis C virus." in: The Journal of infectious diseases, Vol. 201, Issue 9, pp. 1371-80, 2010 (PubMed).

Catalog No. ABIN655818
$324.50
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Plus shipping costs $45.00

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