LOC729993 (Center) antibody

Antigen: LOC729993

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN655834

Additional Information

Gene ID: 729993

UniProt: NP_001138677.1, C9JCE9

Immunogen: This LOC729993 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-198 amino acids from the Central region of human LOC729993.

Isotype: Ig

Description: Other names: Protein shisa-9,SHISA9,

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This LOC729993 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-198 amino acids from the Central region of human LOC729993.

Molecular Weight: 46925 DA

Comments:

Background: SHISA9 is a regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity).

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Cell Signaling, Protein Modifications, Cell Structure, Neurology

Restrictions: For Research Use only

Publications

Product: ODonovan, Craddock, Norton et al.: "Identification of loci associated with schizophrenia by genome-wide association and follow-up." in: Nature genetics, Vol. 40, Issue 9, pp. 1053-5, 2009 (PubMed).

von Engelhardt, Mack, Sprengel et al.: "CKAMP44: a brain-specific protein attenuating short-term synaptic plasticity in the dentate gyrus." in: Science (New York, N.Y.), Vol. 327, Issue 5972, pp. 1518-22, 2010 (PubMed).