KLF4 antibody (Kruppel-Like Factor 4 (Gut)) (AA 394-421)

Details for Product anti-KLF4 Antibody No. ABIN655898, Supplier: Log in to see
Antigen
  • KLF4
  • EZF
  • GKLF
  • biklf
  • biklf-A
  • Gklf
  • Zie
  • Kruppel-like factor 4 (gut)
  • Kruppel-like factor 4a
  • Kruppel-like factor 4
  • KLF4
  • klf4a
  • klf4
  • Klf4
Alternatives
anti-Human KLF4 antibody for Western Blotting
Epitope
AA 394-421, C-Term
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Reactivity
Human
270
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Host
Rabbit
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Clonality (Clone)
Polyclonal ()
Conjugate
This KLF4 antibody is un-conjugated
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Application
Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
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Options
Supplier
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Immunogen This KLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-421 AA from the C-terminal region of human KLF4.
Clone RB14356
Isotype Ig
Specificity This KLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 357-386 amino acids from the C-terminal region of human KLF4.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name KLF4 (KLF4 Antibody Abstract)
Background KLF4 is a transcription factor which acts as both an activator and repressor. Binds the CACCC core sequence. Binds to multiple sites in the 5'-flanking region of its own gene and can activate its own transcription. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.
Synonyms: KLF4,Krueppel-like factor 4,EZF, GKLF
Molecular Weight 54671 Da
Gene ID 9314
UniProt O43474
Research Area Ubiquitin-related antibodies, Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Pathways Peptide Hormone Metabolism, Stem Cell Maintenance
Application Notes WB = 1:1000, IF = 1:10-50, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Kruppel-Like Factor 4 (Gut) (KLF4) (AA 394-421), (C-Term) antibody (ABIN655898) KLF4 Antibody (C-term) (ABIN655898) western blot analysis in K562 cell line lysates (...
Background publications Guan, Xie, Leithäuser, Flossbach, Möller, Wirth, Ushmorov: "KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classic Hodgkin lymphoma." in: Blood, Vol. 116, Issue 9, pp. 1469-78, 2010 (PubMed).

Wong, Hou, Tseng, Chien, Wu, Chen, Ho, Kyo, Teng: "Krüppel-like transcription factor 4 contributes to maintenance of telomerase activity in stem cells." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 9, pp. 1510-7, 2010 (PubMed).

Ohnesorge, Viemann, Schmidt, Czymai, Spiering, Schmolke, Ludwig, Roth, Goebeler, Schmidt: "Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)." in: The Journal of biological chemistry, Vol. 285, Issue 34, pp. 26199-210, 2010 (PubMed).

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