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PCDHGA8 antibody (C-Term)

PCDHGA8 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB31662 unconjugated
Catalog No. ABIN655955
  • Target See all PCDHGA8 Antibodies
    PCDHGA8 (Protocadherin gamma Subfamily A, 8 (PCDHGA8))
    Binding Specificity
    • 7
    • 7
    • 7
    • 1
    • 1
    AA 781-808, C-Term
    Reactivity
    Human
    Host
    • 14
    • 2
    Rabbit
    Clonality
    • 15
    • 1
    Polyclonal
    Conjugate
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    This PCDHGA8 antibody is un-conjugated
    Application
    • 16
    • 13
    • 13
    • 13
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PCDHGA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 781-808 amino acids from the C-terminal region of human PCDHGA8.
    Clone
    RB31662
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PCDHGA8 Primary Antibody
  • Application Notes
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    PCDHGA8 (Protocadherin gamma Subfamily A, 8 (PCDHGA8))
    Alternative Name
    PCDHGA8 (PCDHGA8 Products)
    Synonyms
    PCDH-GAMMA-A8 antibody, PCDHGB5 antibody, mKIAA4054 antibody, protocadherin gamma subfamily A, 8 antibody, PCDHGA8 antibody, Pcdhga8 antibody
    Background
    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
    Molecular Weight
    101480
    Gene ID
    9708
    NCBI Accession
    NP_054723, NP_114477
    UniProt
    Q9Y5G5
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