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FOXA2 antibody (Forkhead Box A2) (AA 380-407)

Details for Product anti-FOXA2 Antibody No. ABIN655970, Supplier: Login to see
Antigen
  • hnf3b
  • tcf3b
  • hnf3beta
  • hnf3-beta
  • FOXA2
  • HNF3B
  • TCF3B
  • HNF-3B
  • ax
  • axl
  • fkd1
  • ik:tdsubc_2g8
  • tdsubc_2g8
  • wu:fe05g04
  • xx:tdsubc_2g8
  • FoxA2-A
  • FoxA2a
  • xFD-3
  • xbeta-1
  • HNF-3b
  • HNF3-beta
  • HNF3beta
  • Hnf-3b
  • Hnf3b
  • Tcf-3b
  • Tcf3b
  • HNF-3BETA
Epitope
AA 380-407, C-Term
33
30
21
19
14
14
12
9
8
6
5
4
3
2
2
2
2
2
2
2
2
1
1
1
Reactivity
Human, Rat (Rattus)
174
29
28
5
2
1
1
1
1
1
1
1
1
Host
Rabbit
99
59
21
Clonality (Clone)
Polyclonal ()
Conjugate
This FOXA2 antibody is un-conjugated
7
7
7
7
6
6
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
159
107
81
50
34
15
11
9
6
4
1
1
1
1
Supplier
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Immunogen This FOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-407 AA from the C-terminal region of human FOXA2.
Clone RB31713
Isotype Ig
Specificity This FOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human FOXA2.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FOXA2 (FOXA2 Antibody Abstract)
Background This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.
Synonyms: FOXA2,Hepatocyte nuclear factor 3-beta,HNF3B, TCF3B
Molecular Weight 48306 DA
Gene ID 3170
NCBI Accession NP_068556
UniProt Q9Y261
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Signaling, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-FOXA2 antibody (Forkhead Box A2) (AA 380-407) (ABIN655970) FOXA2 Antibody (C-term) western blot analysis in MCF-7 cell line and rat stomach tis...
Immunohistochemistry (IHC) image for anti-FOXA2 antibody (Forkhead Box A2) (AA 380-407) (ABIN655970) FOXA2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin ...
Immunofluorescence (IF) image for anti-FOXA2 antibody (Forkhead Box A2) (AA 380-407) (ABIN655970) Confocal immunofluorescent analysis of FOXA2 Antibody (C-term) with Hela cell followe...
Background publications Dayoub, Groitl, Dobner et al.: "Foxa2 (HNF-3beta) regulates expression of hepatotrophic factor ALR in liver cells." in: Biochemical and biophysical research communications, Vol. 395, Issue 4, pp. 465-70, 2010 (PubMed).

Song, Washington, Crawford: "Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer." in: Cancer research, Vol. 70, Issue 5, pp. 2115-25, 2010 (PubMed).

Xing, Cohen, Boerwinkle: "A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels." in: American journal of human genetics, Vol. 86, Issue 3, pp. 440-6, 2010 (PubMed).