Add to Basket
|+1 404 474 4654|
|+1 888 205 9894 (TF)|
Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase 2 (TNKS2) (C-Term) antibody
|Synonyms||Tank2, AA517131, AI662480, 5430432P15Rik, TNKL, TANK2, PARP5B, PARP5C, PARP-5b, PARP-5c, TNKS2|
Alternatives Western Blotting (WB), ELISA
|3 references available|
|Quantity||0.1 mg (0.25 mg/ml) (Variants)|
|Price||280.50 $ Plus shipping costs $45.00|
|Availability||Will be delivered in 2 to 3 Business Days|
|Immunogen||This Tnks2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1133-1164 amino acids from the C-terminal region of human Tnks2.|
|Description||Other names: TNKS2,Tankyrase-2,PARP5B, TANK2, TNKL|
|Characteristics||Purified Rabbit Polyclonal Antibody (Pab)|
|Specificity||This Tnks2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1133-1164 amino acids from the C-terminal region of human Tnks2.|
|Molecular Weight||126918 DA|
Background: TNKS2 may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.
|Application Notes||The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:50~100|
|Buffer||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles|
|Research Area||Translation Factors, Cell Structure, Protein Modifications, Chromatin, Signaling|
|Restrictions||For Research Use only|
|Tnks2 Antibody (C-term) (ABIN656002) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.|
Varadi, Brendle, Brandt et al.: "Polymorphisms in telomere-associated genes, breast cancer susceptibility and prognosis." in: European journal of cancer (Oxford, England : 1990), Vol. 45, Issue 17, pp. 3008-16, 2009 (PubMed).
Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).
Prescott, McGrath, Lee et al.: "Telomere length and genetic analyses in population-based studies of endometrial cancer risk." in: Cancer, Vol. 116, Issue 18, pp. 4275-82, 2010 (PubMed).
|Hosts||Rabbit (7), Goat (6)|
|Reactivities||Human (13), Dog (Canine) (3), Mouse (Murine) (3)|
|Applications||Western Blotting (WB) (12), ELISA (7), Flow Cytometry (FACS) (3), Immunofluorescence (IF) (2), Dot Blot (DB) (1), Immunocytochemistry (ICC) (1), Immunohistochemistry (IHC) (1), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (1)|
|Epitopes||AA 800-900 (2), C-Term (2), C-Term,AA 1133-1164 (1), C-Term,AA 1134-1164 (1), N-Term (1)|