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Details for Product No. ABIN656007

Kruppel-Like Factor 4 (Gut) (KLF4) (AA 283-314), (Center) antibody

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Antigen
Synonyms EZF, GKLF, Zie, Gklf, biklf, biklf-A, KLF4
Epitope
»Alternatives AA 283-314, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN656007
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This KLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-314 AA from the Central region of human KLF4.
Clone RB14337
Isotype Ig
Specificity This KLF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-313 amino acids from the Central region of human KLF4.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name KLF4
Background KLF4 is a transcription factor which acts as both an activator and repressor. Binds the CACCC core sequence. Binds to multiple sites in the 5'-flanking region of its own gene and can activate its own transcription. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development.
Synonyms: KLF4,Krueppel-like factor 4,EZF, GKLF
Molecular Weight 54671 DA
Gene ID 9314
UniProt NP_004226.3, O43474
Research Area Ubiquitin-related antibodies, Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Guan, Xie, Leithäuser et al.: "KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classic Hodgkin lymphoma." in: Blood, Vol. 116, Issue 9, pp. 1469-78, 2010 (PubMed).

Ohnesorge, Viemann, Schmidt et al.: "Erk5 activation elicits a vasoprotective endothelial phenotype via induction of Kruppel-like factor 4 (KLF4)." in: The Journal of biological chemistry, Vol. 285, Issue 34, pp. 26199-210, 2010 (PubMed).

Wong, Hou, Tseng et al.: "Krüppel-like transcription factor 4 contributes to maintenance of telomerase activity in stem cells." in: Stem cells (Dayton, Ohio), Vol. 28, Issue 9, pp. 1510-7, 2010 (PubMed).

Alternatives for antigen "Kruppel-Like Factor 4 (Gut) (KLF4)", type "Antibodies"
Hosts (76), (53), (11)
Reactivities (136), (52), (42), (19), (13), (12), (12), (4), (1), (1), (1), (1)
Applications (119), (69), (29), (28), (24), (10), (10), (6), (4), (3), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (24), (22), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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