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RASGRP2 antibody (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated)) (AA 7-34)

Details for Product anti-RASGRP2 Antibody No. ABIN656117, Supplier: Log in to see
Antigen
  • RASGRP2
  • CALDAG-GEFI
  • CDC25L
  • CalDAG-GEFI
  • Caldaggef1
Epitope
AA 7-34, N-Term
6
4
3
2
2
1
1
1
Reactivity
Human
23
5
5
1
1
Host
Rabbit
16
7
Clonality (Clone)
Polyclonal ()
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
17
10
4
2
2
Supplier
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Immunogen This RASGRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 AA from the N-terminal region of human RASGRP2.
Clone RB32230
Isotype Ig
Specificity This RASGRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human RASGRP2.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RASGRP2 (RASGRP2 Antibody Abstract)
Background The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms: RASGRP2,RAS guanyl-releasing protein 2,CDC25L, MCG7
Molecular Weight 75kd Isoform 2. 69248 Da
Gene ID 10235
UniProt Q7LDG7
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure, Neurology
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-RASGRP2 antibody (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated)) (AA 7-34) (ABIN656117) RASGRP2 Antibody (N-term) (ABIN656117) immunohistochemistry analysis in formalin fixe...
Background publications Eto, Murphy, Kerrigan et al.: "Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 12819-24, 2002 (PubMed).