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VEGF antibody (Vascular Endothelial Growth Factor A) (AA 140-168)

Details for Product anti-VEGFA Antibody No. ABIN656118, Supplier: Login to see
Antigen
  • vegf
  • vegfa
  • wu:fj82c06
  • VEGF
  • vegf-a
  • vpf
  • vefg
  • VEGF-A
  • VPF
  • eVEGF120
  • eVEGF164
  • MVCD1
  • Vegf
  • Vegf120
  • Vegf164
  • Vegf188
  • Vpf
  • VEGF164
Alternatives
anti-Human VEGF antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 140-168, Center
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Reactivity
Human
274
93
89
20
14
12
12
6
2
1
1
Host
Rabbit
266
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25
4
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Clonality (Clone)
Polyclonal ()
Conjugate
This VEGF antibody is un-conjugated
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26
15
5
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Application
Western Blotting (WB)
273
212
64
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22
15
14
14
11
6
3
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2
1
1
1
1
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1
Supplier
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Immunogen This VEGFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 AA from the Central region of human VEGFA.
Clone RB32234
Isotype Ig
Specificity This VEGFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the Central region of human VEGFA.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name VEGFA (VEGFA Antibody Abstract)
Background This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Synonyms: VEGFA,Vascular endothelial growth factor A,VEGF
Molecular Weight 27042 DA
Gene ID 7422
NCBI Accession NP_001020538, NP_001020537
UniProt P15692
Research Area Signaling, Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Pathways RTK Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-VEGF antibody (Vascular Endothelial Growth Factor A) (AA 140-168) (ABIN656118) VEGFA Antibody (Center) (ABIN656118) western blot analysis in K562 cell line lysates ...
Background publications Shrivastava-Ranjan, Rollin, Spiropoulou: "Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin." in: Journal of virology, Vol. 84, Issue 21, pp. 11227-34, 2010 (PubMed).