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Vascular Endothelial Growth Factor A (VEGFA) (AA 140-168), (Center) antibody

Details for Product No. ABIN656118
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Antigen
Synonyms MVCD1, VEGF, VPF, Vpf, Vegf, Vegf120, Vegf164, Vegf188, VEGF-A, VEGF164, eVEGF120, eVEGF164, vegf, vegfa, wu:fj82c06, vegf-a, vpf, vefg
Epitope
AA 140-168, Center
(33), (11), (8), (7), (6), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(292), (116), (103), (59), (57), (57), (39), (29), (4), (4), (3), (3), (2)
Host
Rabbit
(282), (91), (17), (3), (3), (3), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(37), (15), (10), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(306), (212), (104), (88), (49), (28), (26), (24), (21), (15), (12), (9), (8), (8), (4), (3), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 400 µL
Options
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Catalog No. ABIN656118
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This VEGFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 AA from the Central region of human VEGFA.
Clone RB32234
Isotype Ig
Specificity This VEGFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the Central region of human VEGFA.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name VEGFA
Background This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Synonyms: VEGFA,Vascular endothelial growth factor A,VEGF
Molecular Weight 27042 DA
Gene ID 7422
UniProt NP_001020537.2, P15692, NP_001020538.2
Research Area Signaling, Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Vascular Endothelial Growth Factor A (VEGFA) (AA 140-168), (Center) antibody VEGFA Antibody (Center) (ABIN656118) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the VEGFA antibody detected the VEGFA protein (arrow).
Background publications Shrivastava-Ranjan, Rollin, Spiropoulou: "Andes virus disrupts the endothelial cell barrier by induction of vascular endothelial growth factor and downregulation of VE-cadherin." in: Journal of virology, Vol. 84, Issue 21, pp. 11227-34, 2010 (PubMed).

Hosts (282), (91), (17), (3), (3), (3), (1)
Reactivities (292), (116), (103), (59), (57), (57), (39), (29), (4), (4), (3), (3), (2)
Applications (306), (212), (104), (88), (49), (28), (26), (24), (21), (15), (12), (9), (8), (8), (4), (3), (2), (2), (2), (1)
Conjugates (37), (15), (10), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1)
Epitopes (33), (11), (8), (7), (6), (6), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN656118
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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