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Potassium Channel Subfamily K Member 1 (KCNK1) (C-Term), (AA 293-320) antibody

Details for Product No. ABIN656119
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Antigen
Synonyms DPK, HOHO, K2P1, K2p1.1, KCNO1, TWIK-1, TWIK1, Twik, k2p1.1, twik-1, twik1, rabKCNK1, AI788889
Epitope
C-Term, AA 293-320
(18), (8), (8), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(36), (12), (3), (1), (1), (1)
Host
Rabbit
(34), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(37), (25), (10), (2), (1)
Pubmed 3 references available
Quantity 400 µL
Options
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Catalog No. ABIN656119
291.50 $
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Immunogen This KCNK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 AA from the C-terminal region of human KCNK1.
Clone RB32239
Isotype Ig
Specificity This KCNK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-328 amino acids from the C-terminal region of human KCNK1.
Predicted Reactivity Rabbit
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name KCNK1
Background This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity.
Synonyms: KCNK1,Potassium channel subfamily K member 1,HOHO1, KCNO1, TWIK1
Molecular Weight 38143 DA
Gene ID 3775
UniProt O00180, NP_002236.1
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Potassium Channel Subfamily K Member 1 (KCNK1) (C-Term), (AA 293-320) antibody KCNK1 Antibody (C-term) (ABIN656119) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Background publications Zhou, Xu, Xie et al.: "TWIK-1 and TREK-1 are potassium channels contributing significantly to astrocyte passive conductance in rat hippocampal slices." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 26, pp. 8551-64, 2009 (PubMed).

McGeachie, Ramoni, Mychaleckyj et al.: "Integrative predictive model of coronary artery calcification in atherosclerosis." in: Circulation, Vol. 120, Issue 24, pp. 2448-54, 2009 (PubMed).

Feliciangeli, Tardy, Sandoz et al.: "Potassium channel silencing by constitutive endocytosis and intracellular sequestration." in: The Journal of biological chemistry, Vol. 285, Issue 7, pp. 4798-805, 2010 (PubMed).

Validation Images
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