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CHRNA10 antibody (AA 179-206)

CHRNA10 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB32240 unconjugated
Catalog No. ABIN656120
  • Target See all CHRNA10 Antibodies
    CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
    Binding Specificity
    • 7
    • 6
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 179-206
    Reactivity
    • 32
    • 12
    • 6
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 31
    • 2
    Rabbit
    Clonality
    • 31
    • 2
    Polyclonal
    Conjugate
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHRNA10 antibody is un-conjugated
    Application
    • 25
    • 20
    • 18
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    Rat
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CHRNA10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-206 amino acids from the Central region of human CHRNA10.
    Clone
    RB32240
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CHRNA10 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    CHRNA10 (Cholinergic Receptor, Nicotinic, alpha 10 (CHRNA10))
    Alternative Name
    CHRNA10 (CHRNA10 Products)
    Synonyms
    si:dkey-24p1.3 antibody, ALPHA 10 nAChR antibody, cholinergic receptor, nicotinic, alpha polypeptide 10 antibody, cholinergic receptor nicotinic alpha 10 subunit antibody, cholinergic receptor, nicotinic, alpha 10a antibody, neuronal acetylcholine receptor subunit alpha-10 antibody, cholinergic receptor, nicotinic, alpha 10 (neuronal) antibody, Chrna10 antibody, CHRNA10 antibody, chrna10a antibody, LOC100344381 antibody
    Background
    CHRNA10 is an ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.
    Molecular Weight
    49705
    Gene ID
    57053
    NCBI Accession
    NP_065135
    UniProt
    Q9GZZ6
    Pathways
    Sensory Perception of Sound, Synaptic Membrane
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