Solute Carrier Family 25 (Mitochondrial Carrier; Adenine Nucleotide Translocator), Member 6 (SLC25A6) (Center) antibody

Antigen: Solute Carrier Family 25 (Mitochondrial Carrier; Adenine Nucleotide Translocator), Member 6 (SLC25A6)

Synonyms: AAC3, ANT3, ANT3Y, MGC17525, Slc25a6, AW557176, D6Bwg0781e, 4930433D19Rik, 4933433F13Rik, SLC25A6, SLC25A5, SLC25A6P, RGD1560896, wu:fj78b08, si:dkey-21o13.4

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN656122

Additional Information

Alternative name: SLC25A6

Gene ID: 293

UniProt: NP_001627.2, P12236

Immunogen: This SLC25A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-163 amino acids from the Central region of human SLC25A6.

Isotype: Ig

Description: Other names: SLC25A6,ADP/ATP translocase 3,ANT3

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This SLC25A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-163 amino acids from the Central region of human SLC25A6.

Molecular Weight: 32866 DA

Comments:

Background: This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein is implicated in the function of the permability transition pore complex (PTPC), which regulates the release of mitochondrial products that induce apoptosis. The human genome contains several non-transcribed pseudogenes of this gene.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8 deg C for up to 6 months. For long term storage store at -20 deg C in small aliquots to prevent freeze-thaw cycles

Research Area: Apoptosis/Necrosis, Signaling, Phospho-specific antibodies, Cell Structure, Protein Modifications

Restrictions: For Research Use only

Images

Confocal immunofluorescent analysis of SLC25A6 Antibody (Center)(ABIN656122) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Publications

Product: Tu, Yan, Hood et al.: "Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells." in: Molecular & cellular proteomics : MCP, Vol. 6, Issue 4, pp. 575-88, 2007 (PubMed).

Yang, Cheng, Hong et al.: "Adenine nucleotide (ADP/ATP) translocase 3 participates in the tumor necrosis factor induced apoptosis of MCF-7 cells." in: Molecular biology of the cell, Vol. 18, Issue 11, pp. 4681-9, 2007 (PubMed).