RPGR antibody (AA 744-772)

Catalog No. ABIN656160

Product Details anti-RPGR Antibody

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Binding Specificity: AA 744-772

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPGR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RPGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-772 amino acids of human RPGR.

Clone: RB31028

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: RPGR Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for RPGR

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Alternative Name: RPGR (RPGR Products)

Synonyms: xrpgr antibody, COD1 antibody, CORDX1 antibody, CRD antibody, PCDX antibody, RP15 antibody, RP3 antibody, XLRP3 antibody, orf15 antibody, Rp3h antibody, retinitis pigmentosa GTPase regulator antibody, retinitis pigmentosa GTPase regulator S homeolog antibody, Rpgr antibody, RPGR antibody, rpgr antibody, rpgr.S antibody, Bm1_19935 antibody, NAEGRDRAFT_80250 antibody

Background: This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

Molecular Weight: 113387

Gene ID: 6103

NCBI Accession: NP_000319, NP_001030025

UniProt: Q92834