SMPD1 antibody (C-Term)
(1 reference)-
- Target See all SMPD1 Antibodies
- SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
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Binding Specificity
- AA 391-419, C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SMPD1 antibody is un-conjugated
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Predicted Reactivity
- B
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This SMPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the C-terminal region of human SMPD1.
- Clone
- RB31029
- Isotype
- IgG
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anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 319-579) antibody
SMPD1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 70-340) antibodySMPD1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) antibodySMPD1 Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 1-364) antibodySMPD1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4H2 unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 391-419), (C-Term) antibodySMPD1 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 201-300) antibodySMPD1 Reactivity: Human, Mouse, Rat WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 391-419) antibodySMPD1 Reactivity: Human WB, IHC, FACS, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1) (AA 396-445) antibodySMPD1 Reactivity: Human, Mouse, Rat, Cow, Sheep, Dog, Horse, Rabbit, Pig, Bat, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:2000. WB: 1:4000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500. FC: 1:25
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- SMPD1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Expiry Date
- 6 months
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: "Sphingosine mediates TNF?-induced lysosomal membrane permeabilization and ensuing programmed cell death in hepatoma cells." in: Journal of lipid research, Vol. 53, Issue 6, pp. 1134-43, (2012) (PubMed).
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: "Sphingosine mediates TNF?-induced lysosomal membrane permeabilization and ensuing programmed cell death in hepatoma cells." in: Journal of lipid research, Vol. 53, Issue 6, pp. 1134-43, (2012) (PubMed).
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- Target
- SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))
- Alternative Name
- SMPD1 (SMPD1 Products)
- Background
- The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq].
- Molecular Weight
- 69936
- Gene ID
- 6609
- NCBI Accession
- NP_000534, NP_001007594
- UniProt
- P17405
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