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DLL3 antibody (delta Like Protein 3) (AA 545-573)

Details for Product anti-DLL3 Antibody No. ABIN656327, Supplier: Login to see
Antigen
  • SCDO1
  • pu
  • pudgy
Alternatives
anti-Human DLL3 antibody for ELISA
Epitope
AA 545-573, C-Term
40
16
15
5
3
3
3
2
2
1
Reactivity
Human
79
17
1
1
1
Host
Rabbit
79
2
Clonality (Clone)
Polyclonal ()
Conjugate
This DLL3 antibody is un-conjugated
7
7
7
4
4
4
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
63
41
33
23
12
11
9
2
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Immunogen This DLL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 545-573 AA from the C-terminal region of human DLL3.
Clone RB31357
Isotype Ig
Specificity This DLL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 552-583 amino acids from the C-terminal region of human DLL3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DLL3 (DLL3 Antibody Abstract)
Background This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq].
Synonyms: DLL3,Delta-like protein 3,
Molecular Weight 64618 DA
Gene ID 10683
NCBI Accession NP_982353, NP_058637
UniProt Q9NYJ7
Research Area Ubiquitin-related antibodies, Cell Signaling, Cell Structure, Protein Modifications, Cell Cycle
Pathways Notch Signaling
Application Notes WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment DLL3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-DLL3 antibody (delta Like Protein 3) (AA 545-573) (ABIN656327) DLL3 Antibody (C-term) (ABIN656327) immunohistochemistry analysis in formalin fixed a...
Background publications Maisenbacher, Han, Obrien et al.: "Molecular analysis of congenital scoliosis: a candidate gene approach." in: Human genetics, Vol. 116, Issue 5, pp. 416-9, 2005 (PubMed).

Whittock, Ellard, Duncan et al.: "Pseudodominant inheritance of spondylocostal dysostosis type 1 caused by two familial delta-like 3 mutations." in: Clinical genetics, Vol. 66, Issue 1, pp. 67-72, 2004 (PubMed).

Bonafé, Giunta, Gassner et al.: "A cluster of autosomal recessive spondylocostal dysostosis caused by three newly identified DLL3 mutations segregating in a small village." in: Clinical genetics, Vol. 64, Issue 1, pp. 28-35, 2003 (PubMed).