Sterol Carrier Protein 2 (SCP2) (N-Term), (AA 14-43) antibody

Details for Product No. ABIN656448
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Antigen
Synonyms AI586070, D10Ertd73e, OS-4, OS4, SCP2, PLTP, NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX, NSLIPTR, SCPx, AA409774, AA409893, C76618, C79031, ns-LTP
Epitope
N-Term, AA 14-43
(11), (9), (8), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(57), (18), (18), (14), (14), (2)
Host
Rabbit
(48), (6), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(4), (4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(46), (31), (21), (10), (10), (3), (3), (2)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN656448
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Immunogen This SCP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-43 AA from the N-terminal region of human SCP2.
Clone RB31279
Isotype Ig
Specificity This SCP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-43 amino acids from the N-terminal region of human SCP2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SCP2
Background This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.
Synonyms: Non-specific lipid-transfer protein,SCP2,
Molecular Weight 58994 DA
Gene ID 6342
NCBI Accession NP_002970, NP_001007251, NP_001007101, NP_001007100
UniProt P22307
Research Area Signaling, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.49 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment SCP2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Sterol Carrier Protein 2 (SCP2) (N-Term), (AA 14-43) antibody SCP2 Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the SCP2 antibody detected the SCP2 protein (arrow).
anti-Sterol Carrier Protein 2 (SCP2) (N-Term), (AA 14-43) antibody (2) SCP2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SCP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Background publications Rikova, Guo, Zeng et al.: "Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer." in: Cell, Vol. 131, Issue 6, pp. 1190-203, 2007 (PubMed).

Shimada, Miyagawa, Kawashima et al.: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

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