Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2) (Center) antibody

Antigen: Cytoplasmic FMR1 Interacting Protein 2 (CYFIP2)

Synonyms: PIR121, Pir121, AA930218, AU022376, mKIAA1168, 1500004I01Rik, 6430511D02Rik, CYFIP2, cyfip2, pir121, DKFZp459P191

Binding Site: Center

Clonality: Polyclonal

Host: Rabbit

Reactivity: Please enquire

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN656495

Additional Information

Alternative name: CYFIP2

Gene ID: 26999

UniProt: NP_001032410.1, NP_001032409.2, Q96F07, NP_055191.2

Immunogen: This CYFIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-388 amino acids from the Central region of human CYFIP2.

Isotype: Ig

Description: Other names: Cytoplasmic FMR1-interacting protein 2,CYFIP2,KIAA1168, PIR121

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This CYFIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-388 amino acids from the Central region of human CYFIP2.

Molecular Weight: 148399 DA

Comments:

Background: CYFIP2 is involved in T-cell adhesion and TP53/p53-dependent induction of apoptosis. Does not bind RNA.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: CYFIP2 Antibody (Center) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Apoptosis/Necrosis, Translation Factors, Signaling, Phospho-specific antibodies, Cell Structure, Protein Modifications, Neurology

Restrictions: For Research Use only

Images

CYFIP2 Antibody (Center) (ABIN656495) western blot analysis in mouse cerebellum tissue lysates (35ug/lane). This demonstrates the CYFIP2 antibody detected the CYFIP2 protein (arrow).

Publications

Product: Daley, Lemire, Akhabir et al.: "Analyses of associations with asthma in four asthma population samples from Canada and Australia." in: Human genetics, Vol. 125, Issue 4, pp. 445-59, 2009 (PubMed).

Wu, Romieu, Shi et al.: "Evaluation of candidate genes in a genome-wide association study of childhood asthma in Mexicans." in: The Journal of allergy and clinical immunology, Vol. 125, Issue 2, pp. 321-327.e13, 2010 (PubMed).

Zhou, Hong, Jiang et al.: "Analyses of associations between three positionally cloned asthma candidate genes and asthma or asthma-related phenotypes in a Chinese population." in: BMC medical genetics, Vol. 10, pp. 123, 2009 (PubMed).

Anitei, Stange, Parshina et al.: "Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN." in: Nature cell biology, Vol. 12, Issue 4, pp. 330-40, 2010 (PubMed).