Interferon, alpha 7 (IFNa7) (N-Term) antibody

Antigen: Interferon, alpha 7 (IFNa7)

Synonyms: IFNA-J, IFN-alphaJ, Ifa7, IFNA7, CaIFN-alpha 7

Binding Site: N-Term

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: Western Blotting (WB), ELISA

Certificates: ISO 9001:2008

Catalog no.: ABIN656502

Additional Information

Alternative name: IFNA7

Gene ID: 3444

UniProt: P01567, NP_066401.2

Immunogen: This IFNA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-67 amino acids from the N-terminal region of human IFNA7.

Isotype: Ig

Description: Other names: Interferon alpha-7,IFNA7,

Characteristics: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Specificity: This IFNA7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-67 amino acids from the N-terminal region of human IFNA7.

Molecular Weight: 22107 DA

Comments:

Background: Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.

Application Details

Application Notes: The suggested dilution is: ELISA ~~ 1:1,000 Western blotting~~ 1:100~500

Concentration: 0.25 mg/ml

Purification: Purified

Buffer: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: IFNA7 Antibody (N-term) can be refrigerated at 2-8°,C for up to 6 months. For long term storage, place the at -20°,C.

Research Area: Cell Signaling, Protein Modifications, Cell Structure

Restrictions: For Research Use only

Images

IFNA7 Antibody (N-term) (ABIN656502) western blot analysis in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the IFNA7 antibody detected the IFNA7 protein (arrow).

Publications

Product: Ashby, Kehoe, Love: "Kallikrein-related peptidase 6 in Alzheimer's disease and vascular dementia." in: Journal of the American Chemical Society, Vol. 1363, Issue Nucleic acids research, pp. 1-10, 2010

Hussain, Gill, Liao: "Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a large human population." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 16, Issue 10, pp. 853-9, 1997 (PubMed).

Nyman, Tölö, Parkkinen et al.: "Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes." in: The Biochemical journal, Vol. 329 ( Pt 2), pp. 295-302, 1998 (PubMed).