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Details for Product No. ABIN656546

2,3-bisphosphoglycerate Mutase (BPGM) (C-Term), (AA 230-259) antibody

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Antigen
Synonyms DPGM, C86192, AI323730, AL022789, Ab2-098, zgc:92230
Epitope
»Alternatives C-Term, AA 230-259
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 4 references available
Catalog no. ABIN656546
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This BPGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-259 AA from the C-terminal region of human BPGM.
Clone RB32095
Isotype Ig
Specificity This BPGM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-259 amino acids from the C-terminal region of human BPGM.
Predicted Reactivity Monkey
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BPGM
Background 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms: Bisphosphoglycerate mutase,BPGM,
Molecular Weight 30005 DA
Gene ID 669
UniProt P07738, NP_954655.1, NP_001715.1
Research Area Protein Modifications, Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment BPGM Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Fujita, Suzuki, Tada et al.: "Human erythrocyte bisphosphoglycerate mutase: inactivation by glycation in vivo and in vitro." in: Journal of biochemistry, Vol. 124, Issue 6, pp. 1237-44, 1999 (PubMed).

Wang, Wei, Bian et al.: "Crystal structure of human bisphosphoglycerate mutase." in: The Journal of biological chemistry, Vol. 279, Issue 37, pp. 39132-8, 2004 (PubMed).

Wang, Liu, Wei et al.: "Seeing the process of histidine phosphorylation in human bisphosphoglycerate mutase." in: The Journal of biological chemistry, Vol. 281, Issue 51, pp. 39642-8, 2006 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Alternatives for antigen "2,3-bisphosphoglycerate Mutase (BPGM)", type "Antibodies"
Hosts (36)
Reactivities (34), (17), (16), (14), (2), (2), (2), (2), (1)
Applications (26), (15), (10), (7), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (13), (2), (1), (1), (1), (1)
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