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gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4) (AA 333-361), (Center) antibody

Details for Product No. ABIN656594, Supplier: Log in to see
Antigen
  • GABRA4
  • Gabra-4
Epitope
AA 333-361, Center
34
18
16
15
15
7
3
1
1
1
1
1
1
1
Reactivity
Human
87
35
21
10
3
1
1
Host
Rabbit
80
19
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
5
5
5
5
5
5
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
95
59
29
28
8
2
2
1
1
Supplier
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Immunogen This GABRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333-361 AA from the Central region of human GABRA4.
Clone RB31338
Isotype Ig
Specificity This GABRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 340-369 amino acids from the Central region of human GABRA4.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name GABRA4 (GABRA4 Antibody Abstract)
Background GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
Synonyms: Gamma-aminobutyric acid receptor subunit alpha-4,GABRA4,
Molecular Weight 61623 DA
Gene ID 2557
NCBI Accession NP_000800
UniProt P48169
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications, Neurology
Pathways
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.38 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment GABRA4 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-gamma-aminobutyric Acid (GABA) A Receptor, alpha 4 (GABRA4) (AA 333-361), (Center) antibody (ABIN656594) GABRA4 Antibody (Center) (ABIN656594) western blot analysis in NCI-H460 cell line lys...
Background publications Ruaño, Thompson, Kane et al.: "Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?" in: Pharmacogenomics, Vol. 11, Issue 7, pp. 959-71, 2010 (PubMed).