SLC23A1 antibody (N-Term)

Catalog No. ABIN656646

Product Details anti-SLC23A1 Antibody

Target: SLC23A1 (SVCT1) (Sodium Dependent Vitamin C Transporter 1 (SVCT1))

Binding Specificity: AA 1-30, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC23A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SLC23A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SLC23A1.

Clone: RB32316

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000-1:2000. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: SLC23A1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References for anti-SLC23A1 antibody (ABIN656646)

Subramanian, Nabokina, Patton, Marchant, Moradi, Said: "Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 304, Issue 12, pp. G1079-86, (2013) (PubMed).

Target Details for SLC23A1

Target: SLC23A1 (SVCT1) (Sodium Dependent Vitamin C Transporter 1 (SVCT1))

Alternative Name: SLC23A1 (SVCT1 Products)

Synonyms: SLC23A2 antibody, SVCT1 antibody, YSPL3 antibody, D18Ucla2 antibody, Slc23a2 antibody, solute carrier family 23 member 1 antibody, solute carrier family 23 (nucleobase transporters), member 1 antibody, SLC23A1 antibody, Slc23a1 antibody

Background: The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Molecular Weight: 64831

Gene ID: 9963

NCBI Accession: NP_005838, NP_689898

UniProt: Q9UHI7