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ATP1B3 antibody (ATPase, Na+/K+ Transporting, beta 3 Polypeptide) (AA 241-270)

Details for Product anti-ATP1B3 Antibody No. ABIN656673, Supplier: Login to see
Antigen
  • ATPB-3
  • CD298
  • NKAB3S
  • AA409958
  • AI664000
  • AW212096
  • atp1b3
Epitope
AA 241-270, C-Term
17
16
14
9
6
5
2
2
1
1
1
1
1
1
Reactivity
Human
77
8
8
3
1
1
1
1
1
1
1
1
Host
Rabbit
63
18
Clonality (Clone)
Polyclonal ()
Conjugate
This ATP1B3 antibody is un-conjugated
5
3
3
3
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
46
35
25
14
9
8
3
3
2
1
1
Supplier
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Immunogen This ATP1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-270 AA from the C-terminal region of human ATP1B3.
Clone RB32424
Isotype Ig
Specificity This ATP1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-278 amino acids from the C-terminal region of human ATP1B3.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ATP1B3 (ATP1B3 Antibody Abstract)
Background The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq].
Synonyms: Sodium/potassium-transporting ATPase subunit beta-3,ATP1B3,
Molecular Weight 31513 DA
Gene ID 483
NCBI Accession NP_001670
UniProt P54709
Research Area Cell Signaling, Cell Structure, Protein Modifications
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment ATP1B3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ATP1B3 antibody (ATPase, Na+/K+ Transporting, beta 3 Polypeptide) (AA 241-270) (ABIN656673) ATP1B3 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/l...
Immunohistochemistry (IHC) image for anti-ATP1B3 antibody (ATPase, Na+/K+ Transporting, beta 3 Polypeptide) (AA 241-270) (ABIN656673) ATP1B3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin...
Background publications Chi, Valencia, Hu et al.: "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes." in: Journal of proteome research, Vol. 5, Issue 11, pp. 3135-44, 2006 (PubMed).