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DSN1 antibody (DSN1, MIND Kinetochore Complex Component, Homolog (S. Cerevisiae)) (AA 257-286)

Details for Product anti-DSN1 Antibody No. ABIN656747, Supplier: Log in to see
Antigen
  • 1700022L09Rik
  • AW552447
  • C20orf172
  • KNL3
  • MIS13
  • dJ469A13.2
  • hKNL-3
Epitope
AA 257-286, C-Term
19
16
2
2
1
1
1
1
Reactivity
Human
46
14
14
Host
Rabbit
43
3
Clonality (Clone)
Polyclonal ()
Conjugate
This DSN1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
31
18
11
3
2
1
1
Supplier
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Immunogen This DSN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-286 AA from the C-terminal region of human DSN1.
Clone RB32490
Isotype Ig
Specificity This DSN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 264-295 amino acids from the C-terminal region of human DSN1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DSN1 (DSN1 Antibody Abstract)
Background This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants.
Synonyms: Kinetochore-associated protein DSN1 homolog,DSN1,C20orf172, MIS13
Molecular Weight 40067 DA
Gene ID 79980
NCBI Accession NP_001138788, NP_001138787, NP_079194
UniProt Q9H410
Research Area Phospho-specific antibodies, Protein Modifications, Cell Cycle, Chromatin, Signaling, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment DSN1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-DSN1 antibody (DSN1, MIND Kinetochore Complex Component, Homolog (S. Cerevisiae)) (AA 257-286) (ABIN656747) DSN1 Antibody (C-term) (ABIN656747) western blot analysis in MDA-MB231 cell line lysa...
Background publications Yang, Wu, Ward et al.: "Phosphorylation of HsMis13 by Aurora B kinase is essential for assembly of functional kinetochore." in: The Journal of biological chemistry, Vol. 283, Issue 39, pp. 26726-36, 2008 (PubMed).

Cheeseman, Desai: "Molecular architecture of the kinetochore-microtubule interface." in: Nature reviews. Molecular cell biology, Vol. 9, Issue 1, pp. 33-46, 2007 (PubMed).

Kiyomitsu, Obuse, Yanagida: "Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1." in: Developmental cell, Vol. 13, Issue 5, pp. 663-76, 2007 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).