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Single-Minded Homolog 1 (Drosophila) (SIM1) (AA 1-30), (N-Term) antibody

Details for Product No. ABIN656884, Supplier: Login to see
Antigen
  • bHLHe14
  • mSIM1
Epitope
AA 1-30, N-Term
19
17
6
1
1
Reactivity
Human
32
4
4
3
3
3
1
1
Host
Rabbit
27
5
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
26
20
18
3
2
1
1
1
Supplier
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Immunogen This SIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human SIM1.
Clone RB32160
Isotype Ig
Specificity This SIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SIM1.
Predicted Reactivity Fruit Fly (Drosophila melanogaster),Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SIM1 (SIM1 Antibody Abstract)
Background SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.
Synonyms: Single-minded homolog 1,SIM1,BHLHE14
Molecular Weight 85515 DA
Gene ID 6492
NCBI Accession NP_005059
UniProt P81133
Research Area Cell Cycle, Transcription Factors, Signaling, Neurology, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.38 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment SIM1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Single-Minded Homolog 1 (Drosophila) (SIM1) (AA 1-30), (N-Term) antibody (ABIN656884) SIM1 Antibody (N-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane...
Immunohistochemistry (IHC) image for anti-Single-Minded Homolog 1 (Drosophila) (SIM1) (AA 1-30), (N-Term) antibody (ABIN656884) SIM1 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin e...
Background publications Traurig, Mack, Hanson et al.: "Common variation in SIM1 is reproducibly associated with BMI in Pima Indians." in: Diabetes, Vol. 58, Issue 7, pp. 1682-9, 2009 (PubMed).