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Details for Product No. ABIN656910

CTF18, Chromosome Transmission Fidelity Factor 18 Homolog (S. Cerevisiae) (CHTF18) (C-Term), (AA 914-943) antibody

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Antigen
Synonyms 6030457M03Rik, CTF18, Chl12, CHL12, Ctf18, RUVBL, C16orf41, C321D2.2, C321D2.3, C321D2.4, CHTF18, zgc:113153, MGC81266
Epitope
»Alternatives C-Term, AA 914-943
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN656910
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This CHTF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 914-943 AA from the C-terminal region of human CHTF18.
Clone RB32513
Isotype Ig
Specificity This CHTF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 913-943 amino acids from the C-terminal region of human CHTF18.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CHTF18
Background CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1, MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176], Bermudez et al., 2003 [PubMed 12930902]).
Synonyms: Chromosome transmission fidelity protein 18 homolog,CHTF18,C16orf41, CTF18
Molecular Weight 107383 DA
Gene ID 63922
UniProt Q8WVB6, NP_071375.1
Research Area Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Chromatin, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment CHTF18 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Background publications Beausoleil, Jedrychowski, Schwartz et al.: "Large-scale characterization of HeLa cell nuclear phosphoproteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

Matsuoka, Ballif, Smogorzewska et al.: "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1160-6, 2007 (PubMed).

Shiomi, Masutani, Hanaoka et al.: "A second proliferating cell nuclear antigen loader complex, Ctf18-replication factor C, stimulates DNA polymerase eta activity." in: The Journal of biological chemistry, Vol. 282, Issue 29, pp. 20906-14, 2007 (PubMed).

Farina, Shin, Kim et al.: "Studies with the human cohesin establishment factor, ChlR1. Association of ChlR1 with Ctf18-RFC and Fen1." in: The Journal of biological chemistry, Vol. 283, Issue 30, pp. 20925-36, 2008 (PubMed).

Murakami, Takano, Takeo et al.: "Stable interaction between the human proliferating cell nuclear antigen loader complex Ctf18-replication factor C (RFC) and DNA polymerase {epsilon} is mediated by the cohesion-specific subunits, Ctf18, Dcc1, and Ctf8." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34608-15, 2010 (PubMed).

Alternatives for antigen "CTF18, Chromosome Transmission Fidelity Factor 18 Homolog (S. Cerevisiae) (CHTF18)", type "Antibodies"
Hosts (12), (7)
Reactivities (17), (2), (2)
Applications (18), (6), (5), (2), (2), (1), (1), (1), (1)
Epitopes (3), (2), (2), (2), (2), (1)
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