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LARP7 antibody (La Ribonucleoprotein Domain Family, Member 7) (AA 527-556)

Details for Product anti-LARP7 Antibody No. ABIN656914, Supplier: Log in to see
Antigen
  • ALAZS
  • C330027G06Rik
  • D3Wsu161e
  • fa10g04
  • Larp7
  • LARP7
  • PIP7S
  • wu:fa10g04
  • zgc:56476
Epitope
AA 527-556, C-Term
27
17
2
2
2
1
1
1
1
Reactivity
Human
46
11
10
4
2
2
1
Host
Rabbit
46
Clonality (Clone)
Polyclonal ()
Conjugate
This LARP7 antibody is un-conjugated
4
2
2
2
2
2
Application
Western Blotting (WB)
41
24
8
5
2
2
2
2
Supplier
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Immunogen This LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 527-556 AA from the C-terminal region of human LARP7.
Clone RB32547
Isotype Ig
Specificity This LARP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 526-556 amino acids from the C-terminal region of human LARP7.
Predicted Reactivity Mouse (Murine),Monkey,Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name LARP7 (LARP7 Antibody Abstract)
Background LARP7 is a negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Synonyms: La-related protein 7,LARP7,
Molecular Weight 66899 DA
Gene ID 51574
NCBI Accession NP_056269, NP_057732
UniProt Q4G0J3
Research Area Signaling, Phospho-specific antibodies, Protein Modifications, Chromatin, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.44 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment LARP7 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-LARP7 antibody (La Ribonucleoprotein Domain Family, Member 7) (AA 527-556) (ABIN656914) LARP7 Antibody (C-term) (ABIN656914) western blot analysis in WiDr cell line lysates ...
Background publications Tyagi, Pearson, Karn: "Establishment of HIV latency in primary CD4+ cells is due to epigenetic transcriptional silencing and P-TEFb restriction." in: Journal of virology, Vol. 84, Issue 13, pp. 6425-37, 2010 (PubMed).

Kalsi, Kuo, Aliev, Alexander, McMichael, Patterson, Walsh, Zhao, Schuckit, Nurnberger, Edenberg, Kramer, Hesselbrock, Tischfield, Vladimirov, Prescott, Dick, Kendler, Riley: "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts." in: Human molecular genetics, Vol. 19, Issue 12, pp. 2497-506, 2010 (PubMed).

He, Jahchan, Hong, Li, Bayfield, Maraia, Luo, Zhou: "A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis." in: Molecular cell, Vol. 29, Issue 5, pp. 588-99, 2008 (PubMed).