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Stearoyl-CoA Desaturase 5 (SCD5) (AA 147-175), (Center) antibody

Details for Product No. ABIN656967
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Antigen
Epitope
AA 147-175, Center
(8), (6), (2), (1)
Reactivity
Human
(10)
Host
Rabbit
(10)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(10), (7)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN656967
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Immunogen This SCD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 AA from the Central region of human SCD5.
Clone RB32907
Isotype Ig
Specificity This SCD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 146-175 amino acids from the Central region of human SCD5.
Predicted Reactivity Cow (Bovine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name SCD5
Background Stearoyl-CoA desaturase (SCD, EC 1.14.99.5) is an integral membrane protein of the endoplasmic reticulum that catalyzes the formation of monounsaturated fatty acids from saturated fatty acids. SCD may be a key regulator of energy metabolism with a role in obesity and dislipidemia. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 (MIM 604031) and SCD5, have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates (Wang et al., 2005 [PubMed 15907797]).
Synonyms: Stearoyl-CoA desaturase 5,SCD5,ACOD4, SCD4
Molecular Weight 37610 DA
Gene ID 79966
UniProt Q86SK9, NP_001032671.2, NP_079182.2
Research Area Cell Structure, Metabolism
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment SCD5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Stearoyl-CoA Desaturase 5 (SCD5) (AA 147-175), (Center) antibody SCD5 Antibody (Center) (ABIN656967) western blot analysis in MCF-7 cell line lysates (35 µg/lane). This demonstrates the SCD5 antibody detected the SCD5 protein (arrow).
Background publications Jugessur, Shi, Gjessing et al.: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).

Validation Images
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