HIST1H2AB antibody (N-Term)

Catalog No. ABIN656986

Product Details anti-HIST1H2AB Antibody

Target: HIST1H2AB (Histone Cluster 1, H2ab (HIST1H2AB))

Binding Specificity: AA 12-40, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIST1H2AB antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M, Rat, B, X, C, Pr, Zf

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HIST1H2AB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-40 amino acids from the N-terminal region of human HIST1H2AB.

Clone: RB32983

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: HIST1H2AB Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for HIST1H2AB

Target: HIST1H2AB (Histone Cluster 1, H2ab (HIST1H2AB))

Alternative Name: HIST1H2AB (HIST1H2AB Products)

Synonyms: H2A/m antibody, H2AFM antibody, H2A.1 antibody, H2a-53 antibody, histone cluster 1 H2A family member b antibody, histone cluster 1, H2ab antibody, HIST1H2AB antibody, Hist1h2ab antibody

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.

Molecular Weight: 14135

Gene ID: 8335, 3012

NCBI Accession: NP_003504, NP_066390

UniProt: P04908

Pathways: Telomere Maintenance