LZTS1 antibody (N-Term)

Catalog No. ABIN656993

Product Details anti-LZTS1 Antibody

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Binding Specificity: AA 77-105, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LZTS1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This LZTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human LZTS1.

Clone: RB33006

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: LZTS1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for LZTS1

Target: LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))

Alternative Name: LZTS1 (LZTS1 Products)

Synonyms: F37 antibody, FEZ1 antibody, Psdzip70 antibody, LZTS1 antibody, f37 antibody, fez1 antibody, leucine zipper tumor suppressor 1 antibody, leucine zipper, putative tumor suppressor 1 antibody, LZTS1 antibody, Lzts1 antibody, lzts1 antibody

Background: This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.

Molecular Weight: 66613

Gene ID: 11178

NCBI Accession: NP_066300

UniProt: Q9Y250

Pathways: Synaptic Membrane