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RAS, Dexamethasone-Induced 1 (RASD1) (AA 248-277), (C-Term) antibody

Details for Product No. ABIN657026, Supplier: Log in to see
Antigen
  • AGS1
  • DEXRAS1
  • MGC:26290
  • Dexras1
Epitope
AA 248-277, C-Term
17
8
8
4
2
2
1
Reactivity
Mouse (Murine)
19
12
4
2
2
2
Host
Rabbit
25
2
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
22
18
14
2
1
Supplier
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Immunogen This RASD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-277 AA from the C-terminal region of human RASD1.
Clone RB31294
Isotype Ig
Specificity This RASD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-278 amino acids from the C-terminal region of human RASD1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RASD1 (RASD1 Antibody Abstract)
Background This gene encodes a Ras-related protein that is stimulated by dexamethasone. The exact function of this gene is unknown, but it may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. In addition, studies of a similar rat protein suggest that it functions as as a novel physiologic nitric oxide (NO) effector. The gene product belongs to the Ras superfamily of small GTPases.
Synonyms: Dexamethasone-induced Ras-related protein 1,RASD1,AGS1, DEXRAS1
Research Area Signaling, Protein Modifications, Cell Structure, Chromatin
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.28 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-RAS, Dexamethasone-Induced 1 (RASD1) (AA 248-277), (C-Term) antibody (ABIN657026) RASD1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/la...
Immunohistochemistry (IHC) image for anti-RAS, Dexamethasone-Induced 1 (RASD1) (AA 248-277), (C-Term) antibody (ABIN657026) RASD1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin ...
Background publications Nojima, Maruyama, Yasui et al.: "Genomic screening for genes silenced by DNA methylation revealed an association between RASD1 inactivation and dexamethasone resistance in multiple myeloma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 13, pp. 4356-64, 2009 (PubMed).

Lau, Chan, Perkinton et al.: "Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription." in: The Journal of biological chemistry, Vol. 283, Issue 50, pp. 34728-37, 2008 (PubMed).