FGD2 antibody (C-Term)

Catalog No. ABIN657115

Product Details anti-FGD2 Antibody

Target: FGD2 (FYVE, RhoGEF and PH Domain Containing 2 (FGD2))

Binding Specificity: AA 508-537, C-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FGD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-537 amino acids from the C-terminal region of human FGD2.

Clone: RB32867

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for FGD2

Target: FGD2 (FYVE, RhoGEF and PH Domain Containing 2 (FGD2))

Alternative Name: FGD2 (FGD2 Products)

Synonyms: Tcd-2 antibody, Tcd2 antibody, ZFYVE4 antibody, tcs-2 antibody, tcs2 antibody, FYVE, RhoGEF and PH domain containing 2 antibody, FYVE, RhoGEF and PH domain-containing protein 2 antibody, Fgd2 antibody, FGD2 antibody, LOC100460740 antibody, fgd2 antibody

Background: FGD2 activates CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate (By similarity).

Molecular Weight: 74892

NCBI Accession: NP_775829

UniProt: Q7Z6J4