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Insulin-Like Growth Factor I (IGF1) (C-Term) antibody

Antigen

Insulin-Like Growth Factor I (IGF1)

Synonyms Igf-1, Igf-I, C730016P09Rik, IGF1, IGFI, IGF-I, IGFIA, IGF-IB, LOC100136741, igf1, LOC100305062, IGF1A, igf1-A
Binding Site
Alternatives

C-Term

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
2 references available
Certificates ISO 9001:2008
Catalog no. ABIN657136
Quantity 0.1 mg  (0.25 mg/ml)  (Variants)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name IGF1
Isotype Ig
Description Other names: Insulin-like growth factor I,IGF1,IBP1
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This IGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-189 amino acids from the C-terminal region of human IGF1.
Comments

Background: The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Several transcript variants encoding different isoforms have been found for this gene.

Application Details

Concentration 0.25 mg/ml
Purification Purified
Research Area Cell Signaling, Protein Modifications, Cell Cycle, Cell Structure
Restrictions For Research Use only

Publications

Product Canzian, Cox, Setiawan et al.: "Comprehensive analysis of common genetic variation in 61 genes related to steroid hormone and insulin-like growth factor-I metabolism and breast cancer risk in the NCI breast and prostate cancer cohort consortium." in: Human molecular genetics, Vol. 19, Issue 19, pp. 3873-84, 2010 (PubMed).

Li, Yin, Hua et al.: "The reciprocal regulation of gamma-synuclein and IGF-I receptor expression creates a circuit that modulates IGF-I signaling." in: The Journal of biological chemistry, Vol. 285, Issue 40, pp. 30480-8, 2010 (PubMed).