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ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 3 (Hu Antigen C) (ELAVL3) (N-Term) antibody

Antigen

ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 3 (Hu Antigen C) (ELAVL3)

Synonyms HUC, HUCL, PLE21, MGC20653, DKFZp547J036, HuC, elrc, zHuC, id:ibd1248, wu:fb77b03, elrC
Binding Site
Alternatives

N-Term

Clonality Polyclonal
Host
Alternatives

Rabbit

Reactivity
Alternatives

Human

Conjugate
Alternatives Un-conjugated
Application
Alternatives Western Blotting (WB), ELISA
1 reference available
Certificates ISO 9001:2008
Catalog no. ABIN657256
Quantity 0.1 mg  (0.25 mg/ml)
Price 280.50 $   Plus shipping costs $45.00
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Additional Information

Alternative name ELAVL3
Isotype Ig
Description Other names: ELAV-like protein 3,ELAVL3,HUC, PLE21
Characteristics Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Specificity This ELAVL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the N-terminal region of human ELAVL3.
Comments

Background: A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Application Details

Concentration 0.25 mg/ml
Purification Purified
Research Area Cell Cycle, Signaling, Chromatin, Neurology, Cell Structure
Restrictions For Research Use only

Publications

Product Behrends, Jandl, Golbeck et al.: "Novel products of the HUD, HUC, NNP-1 and alpha-internexin genes identified by autologous antibody screening of a pediatric neuroblastoma library." in: International journal of cancer. Journal international du cancer, Vol. 100, Issue 6, pp. 669-77, 2002 (PubMed).

Alternatives

Alternatives for antigen "ELAV (Embryonic Lethal, Abnormal Vision, Drosophila)-Like 3 (Hu Antigen C) (ELAVL3)", type "Antibodies"
Hosts Rabbit (25)
Reactivities Human (25), Rat (Rattus) (23), Mouse (Murine) (22), Cow (Bovine) (20), Dog (Canine) (20), Horse (Equine) (19), Pig (Porcine) (19), Cat (Feline) (1), Chicken (1)
Applications Immunofluorescence (IF) (17), Western Blotting (WB) (9), ELISA (8), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (3), Immunoprecipitation (IP) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (IHC) (1)
Conjugates Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes AA 20-36 (1), N-Term (1)