Delta(4)-Desaturase, Sphingolipid 1 (DEGS1) (N-Term), (AA 1-30) antibody

Details for Product No. ABIN657334
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Antigen
Epitope
N-Term, AA 1-30
(8), (7), (2), (2)
Reactivity
Human
(31), (16), (16), (13), (12), (1), (1), (1)
Host
Rabbit
(28), (4)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(20), (10), (10), (7), (5)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN657334
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Immunogen This DEGS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human DEGS1.
Clone RB33441
Isotype Ig
Specificity This DEGS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DEGS1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DEGS1
Background This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.
Synonyms: Sphingolipid delta(4)-desaturase DES1,DEGS1,DES1, MLD
Research Area Phospho-specific antibodies, Cell Structure, Protein Modifications, Metabolism
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.45 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
anti-Delta(4)-Desaturase, Sphingolipid 1 (DEGS1) (N-Term), (AA 1-30) antibody DEGS1 Antibody (N-term) (ABIN657334) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the DEGS1 antibody detected the DEGS1 protein (arrow).
Background publications Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

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