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Tubulin Folding Cofactor C (TBCC) (AA 20-49), (N-Term) antibody

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Synonyms CFC, 2810055C19Rik
AA 20-49, N-Term
(15), (15), (4), (3), (2), (1), (1), (1), (1)
Mouse (Murine)
(46), (27), (8), (3)
(41), (20)
Clonality (Clone)
Polyclonal ()
(5), (5), (5), (2), (2), (2)
Western Blotting (WB)
(48), (24), (13), (8), (4), (2), (1)
Pubmed 3 references available
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Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This TBCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 AA from the N-terminal region of human TBCC.
Clone RB33319
Isotype Ig
Specificity This TBCC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-49 amino acids from the N-terminal region of human TBCC.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name TBCC (TBCC Antibody Abstract)
Background Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex, interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
Synonyms: Tubulin-specific chaperone C,TBCC,
Molecular Weight 39248 DA
Gene ID 6903
NCBI Accession NP_003183
UniProt Q15814
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.36 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment TBCC Antibody (N-term ) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Tubulin Folding Cofactor C (TBCC) (AA 20-49), (N-Term) antibody (ABIN657398) TBCC Antibody (N-term ) (ABIN657398) western blot analysis in mouse spleen tissue lys...
Background publications Hage-Sleiman, Herveau, Matera et al.: "Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells." in: BMC cancer, Vol. 10, pp. 135, 2010 (PubMed).

Mungall, Palmer, Sims et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, 2003 (PubMed).

Bartolini, Bhamidipati, Thomas et al.: "Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C." in: The Journal of biological chemistry, Vol. 277, Issue 17, pp. 14629-34, 2002 (PubMed).

Catalog No. ABIN657398
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