Ubiquitin Specific Peptidase 40 (USP40) (N-Term), (AA 63-91) antibody

Details for Product No. ABIN657495
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Antigen
Epitope
N-Term, AA 63-91
(7), (6), (1), (1)
Reactivity
Mouse (Murine)
(7), (6)
Host
Rabbit
(13)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(12), (8), (6)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN657495
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Immunogen This USP40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 AA from the N-terminal region of human USP40.
Clone RB32563
Isotype Ig
Specificity This USP40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the N-terminal region of human USP40.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name USP40
Background Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).
Synonyms: Ubiquitin carboxyl-terminal hydrolase 40,USP40,
Molecular Weight 57kd Isoform 4(mouse). 140130 DA
Gene ID 55230
NCBI Accession NP_060688
UniProt Q9NVE5
Research Area Phospho-specific antibodies, Protein Modifications, Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment USP40 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Ubiquitin Specific Peptidase 40 (USP40) (N-Term), (AA 63-91) antibody USP40 Antibody (N-term) (ABIN657495) western blot analysis in mouse spleen tissue lysates (35 µg/lane). This demonstrates the USP40 antibody detected the USP40 protein (arrow).
Background publications Puente, Sánchez, Overall et al.: "Human and mouse proteases: a comparative genomic approach." in: Nature reviews. Genetics, Vol. 4, Issue 7, pp. 544-58, 2003 (PubMed).

Quesada, Díaz-Perales, Gutiérrez-Fernández et al.: "Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases." in: Biochemical and biophysical research communications, Vol. 314, Issue 1, pp. 54-62, 2004 (PubMed).

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