Dolichyl Pyrophosphate Phosphatase 1 (DOLPP1) (C-Term), (AA 207-236) antibody

Details for Product No. ABIN657579
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Antigen
Synonyms LSFR2, AB030189, 0610011H20Rik, zgc:101585, lsfr2, DOLPP1
Epitope
C-Term, AA 207-236
(2), (1)
Reactivity
Mouse (Murine)
(3), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(4)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB)
(4)
Pubmed 4 references available
Catalog no. ABIN657579
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This DOLPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 AA from the C-terminal region of human DOLPP1.
Clone RB33347
Isotype Ig
Specificity This DOLPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the C-terminal region of human DOLPP1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DOLPP1
Background DOLPP1 is required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate (By similarity).
Synonyms: Dolichyldiphosphatase 1,DOLPP1,
Molecular Weight 27031 DA
Gene ID 57171
UniProt Q86YN1, NP_001129389.1, NP_065171.2
Research Area Cell Structure, Metabolism
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment DOLPP1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Dolichyl Pyrophosphate Phosphatase 1 (DOLPP1) (C-Term), (AA 207-236) antibody DOLPP1 Antibody (C-term) (ABIN657579) western blot analysis in mouse stomach tissue lysates (35 µg/lane). This demonstrates the DOLPP1 antibody detected the DOLPP1 protein (arrow).
Background publications Wedgwood, Strominger: "Enzymatic activities in cultured human lymphocytes that dephosphorylate dolichyl pyrophosphate and dolichyl phosphate." in: The Journal of biological chemistry, Vol. 255, Issue 3, pp. 1120-3, 1980 (PubMed).

Gilley, Fried: "Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes." in: Human molecular genetics, Vol. 8, Issue 7, pp. 1313-20, 1999 (PubMed).

Rush, Cho, Jiang et al.: "Identification and characterization of a cDNA encoding a dolichyl pyrophosphate phosphatase located in the endoplasmic reticulum of mammalian cells." in: The Journal of biological chemistry, Vol. 277, Issue 47, pp. 45226-34, 2002 (PubMed).

Humphray, Oliver, Hunt et al.: "DNA sequence and analysis of human chromosome 9...." in: Nature, Vol. 429, Issue 6990, pp. 369-74, 2004 (PubMed).

Hosts (4)
Reactivities (3), (1), (1), (1), (1), (1), (1)
Applications (4)
Epitopes (2), (1)
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