You are viewing an incomplete version of our website. Please click to reload the website as full version.

MEN1 (AA 3-32), (N-Term) antibody

Details for Product No. ABIN657669, Supplier: Login to see
Antigen
Epitope
AA 3-32, N-Term
10
7
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
37
10
8
Host
Rabbit
35
3
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
35
18
11
10
2
1
1
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This MEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-32 AA from the N-terminal region of human MEN1.
Clone RB33738
Isotype Ig
Specificity This MEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human MEN1.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Background This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.
Synonyms: Menin,MEN1,SCG2
Molecular Weight 67993 DA
Gene ID 4221
NCBI Accession NP_570712, NP_570711, NP_000235, NP_570716
UniProt O00255
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Pathways
Application Notes WB = 1:1000, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.26 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment MEN1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-MEN1 (AA 3-32), (N-Term) antibody (ABIN657669) MEN1 Antibody (N-term) (ABIN657669) western blot analysis in CEM cell line lysates (3...
Product cited in: Fang, Xia, Mahalingam et al.: "MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair." in: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2635-47, 2013 (PubMed).

Background publications Stratakis, Tichomirowa, Boikos et al.: "The role of germline AIP, MEN1, PRKAR1A, CDKN1B and CDKN2C mutations in causing pituitary adenomas in a large cohort of children, adolescents, and patients with genetic syndromes." in: Clinical genetics, Vol. 78, Issue 5, pp. 457-63, 2010 (PubMed).