MEN1 (N-Term), (AA 3-32) antibody

Details for Product No. ABIN657669
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Epitope
N-Term, AA 3-32
(5), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(14), (10), (9)
Host
Rabbit
(15)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Immunofluorescence (IF)
(15), (8), (8), (2), (1)
Pubmed 1 reference available
Quantity 400 µL
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN657669
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This MEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 3-32 AA from the N-terminal region of human MEN1.
Clone RB33738
Isotype Ig
Specificity This MEN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-32 amino acids from the N-terminal region of human MEN1.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Background This gene encodes menin, a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1. In vitro studies have shown menin is localized to the nucleus, possesses two functional nuclear localization signals, and inhibits transcriptional activation by JunD, however, the function of this protein is not known. Two messages have been detected on northern blots but the larger message has not been characterized. Alternative splicing results in multiple transcript variants.
Synonyms: Menin,MEN1,SCG2
Molecular Weight 67993 DA
Gene ID 4221
NCBI Accession NP_570712, NP_570711, NP_000235, NP_570716
UniProt O00255
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.26 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment MEN1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-MEN1 (N-Term), (AA 3-32) antibody MEN1 Antibody (N-term) (ABIN657669) western blot analysis in CEM cell line lysates (35 µg/lane). This demonstrates the MEN1 antibody detected the MEN1 protein (arrow).
Background publications Stratakis, Tichomirowa, Boikos et al.: "The role of germline AIP, MEN1, PRKAR1A, CDKN1B and CDKN2C mutations in causing pituitary adenomas in a large cohort of children, adolescents, and patients with genetic syndromes." in: Clinical genetics, Vol. 78, Issue 5, pp. 457-63, 2010 (PubMed).

Validation Images
Did you look for something else?
back to top