B-Cell CLL/lymphoma 2 (BCL2) (AA 86-114), (Center) antibody

Details for Product No. ABIN657744
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Antigen
Synonyms Bcl-2, PPP1R50, bcl-2, BCL-2
Epitope
AA 86-114, Center
(43), (42), (32), (21), (21), (19), (13), (13), (6), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(400), (149), (121), (55), (36), (36), (14), (12), (3), (2)
Host
Rabbit
(325), (119), (8), (5), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(15), (14), (7), (7), (7), (7), (7), (7), (7), (7), (7), (6), (1), (1), (1), (1)
Application
Western Blotting (WB)
(300), (153), (122), (122), (81), (78), (70), (48), (47), (45), (12), (4), (3), (2), (2), (2), (2), (2), (1), (1)
Pubmed 1 reference available
Catalog no. ABIN657744
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This BCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 AA from the Central region of human BCL2.
Clone RB32981
Isotype Ig
Specificity This BCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the Central region of human BCL2.
Predicted Reactivity Cow (Bovine),Hamster,Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BCL2
Background This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].
Synonyms: Apoptosis regulator Bcl-2,BCL2,
Molecular Weight 26266 DA
Gene ID 596
UniProt P10415, NP_000624.2
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Structure, Protein Modifications, Cancer, Chromatin, Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment BCL2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-B-Cell CLL/lymphoma 2 (BCL2) (AA 86-114), (Center) antibody BCL2 Antibody (Center) (ABIN657744) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the BCL2 antibody detected the BCL2 protein (arrow).
Background publications Feng, Stachura, White et al.: "T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation." in: Cancer cell, Vol. 18, Issue 4, pp. 353-66, 2010 (PubMed).

Hosts (325), (119), (8), (5), (1)
Reactivities (400), (149), (121), (55), (36), (36), (14), (12), (3), (2)
Applications (300), (153), (122), (122), (81), (78), (70), (48), (47), (45), (12), (4), (3), (2), (2), (2), (2), (2), (1), (1)
Conjugates (15), (14), (7), (7), (7), (7), (7), (7), (7), (7), (7), (6), (1), (1), (1), (1)
Epitopes (43), (42), (32), (21), (21), (19), (13), (13), (6), (6), (5), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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