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BCL2 antibody (B-Cell CLL/lymphoma 2) (AA 86-114)

Details for Product anti-BCL2 Antibody No. ABIN657744, Supplier: Login to see
Antigen
  • AW986256
  • Bcl-2
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • PPP1R50
  • BCL-2
  • bcl-2
  • Bcl2
Alternatives
anti-Human BCL2 antibody for Immunohistochemistry (Frozen Sections)
Epitope
AA 86-114, Center
78
74
54
50
49
43
23
23
17
17
14
14
14
13
13
13
13
12
11
9
7
4
4
4
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
680
199
150
17
9
7
4
3
2
2
1
1
Host
Rabbit
497
242
20
6
2
2
2
Clonality (Clone)
Polyclonal ()
Conjugate
This BCL2 antibody is un-conjugated
37
33
27
24
18
14
11
10
8
6
6
6
6
6
6
3
1
1
1
1
Application
Western Blotting (WB)
485
275
241
145
139
136
118
68
49
42
36
11
10
10
8
8
5
1
1
1
1
1
Supplier
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Immunogen This BCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 AA from the Central region of human BCL2.
Clone RB32981
Isotype Ig
Specificity This BCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-114 amino acids from the Central region of human BCL2.
Predicted Reactivity Cow (Bovine),Hamster,Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name BCL2 (BCL2 Antibody Abstract)
Background This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].
Synonyms: Apoptosis regulator Bcl-2,BCL2,
Molecular Weight 26266 DA
Gene ID 596
NCBI Accession NP_000624
UniProt P10415
Research Area Apoptosis/Necrosis, Phospho-specific antibodies, Cell Structure, Protein Modifications, Cancer, Chromatin, Signaling
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment BCL2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-BCL2 antibody (B-Cell CLL/lymphoma 2) (AA 86-114) (ABIN657744) BCL2 Antibody (Center) (ABIN657744) western blot analysis in mouse heart tissue lysat...
Background publications Feng, Stachura, White et al.: "T-lymphoblastic lymphoma cells express high levels of BCL2, S1P1, and ICAM1, leading to a blockade of tumor cell intravasation." in: Cancer cell, Vol. 18, Issue 4, pp. 353-66, 2010 (PubMed).