CENPA antibody (AA 82-110)

Catalog No. ABIN657764

Product Details anti-CENPA Antibody

Target: CENPA (Centromere Protein A (CENPA))

Binding Specificity: AA 82-110

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPA antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: B, Ha

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CENPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-110 amino acids from the Central region of human CENPA.

Clone: RB33757

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: CENPA Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for CENPA

Target: CENPA (Centromere Protein A (CENPA))

Alternative Name: CENPA (CENPA Products)

Synonyms: CENP-A antibody, CenH3 antibody, Cenp-A antibody, cenpx antibody, cenp-a antibody, sim2 antibody, Cenp-a antibody, RGD1563607 antibody, CENPA antibody, centromere protein A antibody, centromere protein-A antibody, centromeric histone-3 like protein antibody, centromere-specific histone H3 CENP-A antibody, cenp-A antibody, centromere protein A L homeolog antibody, histone H3-like centromeric protein A antibody, CENPA antibody, Cenpa antibody, CENP-A antibody, cenpa antibody, cenp-A antibody, cnp1 antibody, HAN_3g422 antibody, Cenp-a antibody, cenpa.L antibody, CMU_016480 antibody

Background: Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].

Molecular Weight: 15991

Gene ID: 1058

NCBI Accession: NP_001035891, NP_001800

UniProt: P49450

Pathways: Chromatin Binding, Maintenance of Protein Location